WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB

Our group aims to regulate cell function and fate via applying biomaterial cues (chemical and topographical micro/nanopatterning, surface energy tuning) and mechanical signals (fluid flow-induced shear stress, stretch, impulsive pressurization) and through co-regulatory effects from biomaterial and mechanical signals.  Further, by integrating molecular engineering (RNA interference or overexpression) of key signaling molecules, e.g., FAK, ROCK, cadherin, and NF-κB, we aim to reveal the role of focal adhesion, cytoskeletal tension, cell-cell interaction, and immune response in cells sensing and responding to biomaterials and mechanical signals.  The crosstalk between extracellular milieus and cell signaling cascades in cell-biomaterial interaction and mechanotransduction revealed through our study will provide high impact mechanistic data for biomaterials science, mechanobiology, and regenerative medicine (see more RESEARCH).

Dr. Lim is awarded an AO Foundation Grant for the project studying "Controlling Nanotopography-ECM Environment for Enhanced Bone Formation with hMSCs" (see more NEWS).

For more information, please contact Dr. Jung Yul Lim (jlim4@unl.edu, 402-472-2480, W317.3 Nebraska Hall) or lab (402-472-2485, 129 Scott Engineering Center).

Link to:
Dept. of Mechanical and Materials Engineering (formerly EM & ME)
College of Engineering
University of Nebraska-Lincoln