WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB
Our group aims to regulate cell function and fate via applying biomaterial cues (chemical and topographical micro/nanopatterning, surface energy tuning) and mechanical signals (fluid flow-induced shear, mechanical stretch, impulsive pressurization) and through co-regulation from biomaterials and mechanical signals. Further, by integrating molecular engineering (RNA interference or overexpression) of key signaling molecules, e.g., FAK, ROCK, Cadherin, and NF-κB, we aim to reveal the role of focal adhesion, cytoskeletal tension, cell-cell interaction, and immune response in cells sensing and responding to biomaterials and mechanical signals. The crosstalk between engineered extracellular environments and cell signaling cascades in cell-biomaterial interaction and mechanotransduction revealed through our study will provide high impact mechanistic data for biomaterials science, mechanobiology, and regenerative medicine (see more RESEARCH).
Dr. Lim is awarded an American Heart Association (AHA) Scientist Development Grant to investigate "Mechanical-Biochemical Synergistic Inhibition of Adipogenesis" (see more NEWS).
For more information, please contact Dr. Jung Yul Lim (email@example.com, 402-472-2480, W317.3 Nebraska Hall) or lab (402-472-2485, 129 Scott Engineering Center).
Dept. of Mechanical and Materials Engineering; Faculty Page
College of Engineering
University of Nebraska-Lincoln
UNMC Regenerative Medicine Program; Faculty Page