WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB
Our group investigates cellular sensing and response to biomaterial substrate micro/nanopatterns and mechanical loading cues (mechanical stretch, flow shear). Mechanistically, our group aims to identify the regulatory role of focal adhesion, cytoskeleton, cytoskeleton-nucleus linkage, cell-cell junction, and associated mechanosensing effectors - FAK, ROCK, LINC, Cadherin, and YAP - in cell-biomaterial interaction and cell mechanotransduction. Advanced understanding of cell adaptation to mechanophysical milieus for stem cells, adipocytes, and cancer cells achieved through our group's research will provide high impact mechanistic data for developmental mechanobiology, metabolic homeostasis, and cancer metastasis. See more RESEARCH.
Dr. Lim has received a NIH COBRE NPOD Project Leader Grant to investigate innovative adipocyte mechanical load adaptation for metabolic regulation. See more NEWS.
For more information, please contact Dr. Jung Yul Lim (email@example.com, 402-472-2480, W317.3 Nebraska Hall) or the lab (D217E Engineering Research Center).
Dept. of Mechanical and Materials Engineering; Faculty Page
College of Engineering
University of Nebraska-Lincoln
UNMC Regenerative Medicine Program; Faculty Page