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WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB

Our group investigates cellular sensing and response to biomaterial substrate micro/nanopatterns and  mechanical loading cues (mechanical stretch, flow shear).  Mechanistically, our group aims to identify the regulatory role of focal adhesion, cytoskeleton, cytoskeleton-nucleus linkage, cell-cell junction, and associated mechanosensing effectors - FAK, ROCK, LINC, Cadherin, and YAP - in cell-biomaterial interaction and cell mechanotransduction.  Advanced understanding of cell adaptation to mechanophysical milieus for stem cells, adipocytes, and cancer cells achieved through our group's research will provide high impact mechanistic data for developmental mechanobiology, metabolic homeostasis, and cancer metastasis.  See more RESEARCH.

Dr. Lim is awarded a NE DHHS Stem Cell Research Project grant entitled “Flow Shear-Induced YAP/TAZ Mechanosensing in MSCs (PI: Lim).”  See more NEWS.

For more information, please contact Dr. Jung Yul Lim ([email protected], 402-472-2480, W317.3 Nebraska Hall) or the lab (D217E Engineering Research Center).

Link to:
Dept. of Mechanical and Materials Engineering; Faculty Page 
College of Engineering
University of Nebraska-Lincoln
UNMC Regenerative Medicine Program; Faculty Page