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WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB

Our group aims to direct cell function and fate via applying biomaterial cues (chemical and topographical micro/nano-substrates, surface energy tuning, etc.) and mechanical loading signals (mechanical stretch, fluid shear, etc.) and through biomaterial-mechanical loading co-control.  Further, by investigating key mechano-signaling molecules, including FAK, ROCK, Nesprin, Cadherin, and NF-κB, we aim to reveal the regulatory role of focal adhesion, cytoskeletal tension, cytoskeleton-nucleoskeleton link, cell-cell junction, and immune response in cells sensing and responding to biomaterial and mechanical loading environments.  Our investigation of the engineered extracellular milieus and molecular signaling cascades in cell-biomaterial interaction and cellular mechanotransduction will provide high impact mechanistic data for biomaterials science, mechanobiology, and regenerative medicine.  See more RESEARCH.

Dr. Lim received a NE DHHS Stem Cell Research Project grant titled "Role of YAP Mechanotransduction in MSC Fate Decision (PI: Lim)."  See more NEWS.

For more information, please contact Dr. Jung Yul Lim (jlim4@unl.edu, 402-472-2480, W317.3 Nebraska Hall) or the lab (402-472-2485, 129 Scott Engineering Center).

Link to:
Dept. of Mechanical and Materials Engineering; Faculty Page
College of Engineering
University of Nebraska-Lincoln
UNMC Regenerative Medicine Program; Faculty Page