WELCOME TO BIOMATERIALS & MECHANOTRANSDUCTION LAB
Our group aims to direct cell function and fate via biomaterial cues (chemical and topographical micro- and nano-patterned substrates) and mechanical loading signals (mechanical stretch, fluid shear) and through biomaterial-mechanical co-control. Further, by investigating key mechano-signaling molecules, including FAK, ROCK, Nesprin, Cadherin, and NF-κB, we aim to reveal the regulatory role of focal adhesion, cytoskeletal tension, cytoskeleton-nucleoskeleton link, cell-cell junction, and immune response in cells sensing and responding to biomaterial and mechanical loading environments. Our investigation of the engineered extracellular milieus and molecular signaling cascades in cell-biomaterial interaction and cell mechanotransduction will provide high impact mechanistic data for biomaterials science, mechanobiology, and regenerative medicine. See more RESEARCH.
Dr. Lim has received a NIH COBRE NPOD Project Leader Grant titled "Adipocyte Mechanotransduction and Insulin Signaling (PI: Lim)." See more NEWS.
For more information, please contact Dr. Jung Yul Lim (email@example.com, 402-472-2480, W317.3 Nebraska Hall) or the lab (D217E Engineering Research Center).
Dept. of Mechanical and Materials Engineering; Faculty Page
College of Engineering
University of Nebraska-Lincoln
UNMC Regenerative Medicine Program; Faculty Page